I think this printed touchpad frame causes a grounding/static issue. It started completely dieing on me and would not come back. First time it was dead for 4 days until a reset brought it back. Since then it appears a motherboard reset will fix it.
I originally reported it here, with all the details:
FrameworkComputer/SoftwareFirmwareIssueTracker#164
When I have some time, I'm going to experiment with trying to ground it better, which I think is the cause. I have metal strip like this that I will try.