diff --git a/R/utils_groupcomparison.R b/R/utils_groupcomparison.R
index c7713e42..f082bc32 100644
--- a/R/utils_groupcomparison.R
+++ b/R/utils_groupcomparison.R
@@ -140,7 +140,8 @@ getSamplesInfo = function(summarization_output) {
                                        is_single_subject, has_tech_replicates) {
     
     if ("Variance" %in% colnames(input) & !all(is.na(input$Variance))){
-        weight_input = 1/input$Variance
+        unnormalized_weight_input = 1/input$Variance
+        weight_input = unnormalized_weight_input / mean(unnormalized_weight_input)
     } else {
         weight_input = NULL
     }