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Right now, the output of MSstatsResponse is not compatible with the functions of network visualization. The input of network visualization is typically a table with the following columns:
- Protein
- log2FC
- adj.pvalue
MSstatsResponse outputs the columns
- Protein
- Fstatistic (magnitude of how significant the response is)
- IC50 (dose amount in which the response goes to 50%)
- adj.pvalue
We also know if the response is increasing or decreasing.
Update: Sarah mentioned we should add a log2FC column in the output of MSstatsResponse, indicating the estimated log2FC change between control and the last timepoint/dose.
Subtasks
- Meet with Sarah
- Add the log2FC column in output of MSstatsResponse based on the description above.
- Verify MSstatsShiny network visualization runs adequately after creating dose response curves.
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