diff --git a/changes/3345.bugfix.rst b/changes/3345.bugfix.rst
new file mode 100644
index 0000000000..667bb89314
--- /dev/null
+++ b/changes/3345.bugfix.rst
@@ -0,0 +1 @@
+Window visibility and focus events in the web backend no longer raise errors when the browser window loses focus
diff --git a/web/src/toga_web/libs.py b/web/src/toga_web/libs.py
index 669230a680..b98eb8abdc 100644
--- a/web/src/toga_web/libs.py
+++ b/web/src/toga_web/libs.py
@@ -4,15 +4,12 @@
 except ModuleNotFoundError:
     # To ensure the code can be imported, provide a js symbol as a fallback
     js = None
-
-
 try:
-    # Try to import pyodide from the PyScript namespace
     import pyodide
 except ModuleNotFoundError:
-    # To ensure the code can be imported, provide a pyodide symbol as a fallback
     pyodide = None
 
+from pyscript.web import document
 
 create_proxy = pyodide.ffi.create_proxy if pyodide else lambda f: f
 
@@ -43,7 +40,7 @@ def create_element(
         events or methods.
     :returns: A newly created DOM element.
     """
-    element = js.document.createElement(tag)
+    element = document.createElement(tag)
 
     if id:
         element.id = id
diff --git a/web/src/toga_web/window.py b/web/src/toga_web/window.py
index 9eadb9edd1..0ebdf897c8 100644
--- a/web/src/toga_web/window.py
+++ b/web/src/toga_web/window.py
@@ -1,7 +1,7 @@
 from toga.command import Group, Separator
 from toga.constants import WindowState
 from toga.types import Position, Size
-from toga_web.libs import create_element, js
+from toga_web.libs import create_element, create_proxy, js
 
 from .screens import Screen as ScreenImpl
 
@@ -21,9 +21,15 @@ def __init__(self, interface, title, position, size):
         app_placeholder = js.document.getElementById("app-placeholder")
         app_placeholder.appendChild(self.native)
 
-        js.document.body.onfocus = self.dom_on_gain_focus
-        js.document.body.onblur = self.dom_on_lose_focus
-        js.document.addEventListener("visibilitychange", self.dom_on_visibility_change)
+        js.document.body.addEventListener(
+            "focus", create_proxy(self.dom_on_gain_focus), True
+        )
+        js.document.body.addEventListener(
+            "blur", create_proxy(self.dom_on_lose_focus), True
+        )
+        js.document.addEventListener(
+            "visibilitychange", create_proxy(self.dom_on_visibility_change)
+        )
 
         self.set_title(title)
 
@@ -44,11 +50,10 @@ def dom_on_lose_focus(self, event):
         self.interface.on_lose_focus()
 
     def dom_on_visibility_change(self, event):
-        if hasattr(js.document, "hidden"):
-            if js.document.visibilityState == "visible":
-                self.interface.on_show()
-            else:
-                self.interface.on_hide()
+        if js.document.visibilityState == "visible":
+            self.interface.on_show()
+        else:
+            self.interface.on_hide()
 
     ######################################################################
     # Window properties