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<!DOCTYPE html>
<html lang="en">
<head>
<meta charset="UTF-8">
<meta name="viewport" content="width=device-width, initial-scale=1.0">
<title>Clinical Trial Timeline Player</title>
<!-- Bootstrap 5 CSS -->
<link href="https://cdn.jsdelivr.net/npm/bootstrap@5.3.2/dist/css/bootstrap.min.css" rel="stylesheet">
<!-- Bootstrap Icons -->
<link rel="stylesheet" href="https://cdn.jsdelivr.net/npm/bootstrap-icons@1.11.1/font/bootstrap-icons.css">
<style>
body {
background: linear-gradient(135deg, #667eea 0%, #764ba2 100%);
min-height: 100vh;
padding: 20px 0;
font-family: -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, sans-serif;
}
.main-container {
max-width: 1400px;
margin: 0 auto;
padding: 20px;
}
.page-header {
background: rgba(255, 255, 255, 0.95);
border-radius: 15px;
padding: 20px;
margin-bottom: 15px;
box-shadow: 0 10px 40px rgba(0,0,0,0.2);
}
.page-header h1 {
color: #2d3748;
font-weight: 700;
margin-bottom: 5px;
font-size: 28px;
}
.page-header p {
color: #718096;
margin-bottom: 0;
font-size: 14px;
}
.player-container {
background: rgba(255, 255, 255, 0.95);
border-radius: 15px;
padding: 20px;
box-shadow: 0 10px 40px rgba(0,0,0,0.2);
}
.visualization-area {
background: linear-gradient(135deg, #f8f9fa 0%, #e9ecef 100%);
border-radius: 12px;
padding: 20px;
margin-bottom: 15px;
min-height: 400px;
position: relative;
overflow: hidden;
}
.timeline-display {
display: flex;
flex-direction: column;
align-items: center;
justify-content: flex-start;
min-height: 360px;
}
.current-event {
text-align: center;
animation: fadeIn 0.5s ease-in;
}
@keyframes fadeIn {
from { opacity: 0; transform: translateY(20px); }
to { opacity: 1; transform: translateY(0); }
}
.event-number {
font-size: 12px;
color: #718096;
font-weight: 600;
margin-bottom: 5px;
}
.event-id {
font-size: 14px;
color: #4a5568;
font-family: 'Courier New', monospace;
margin-bottom: 8px;
}
.event-label {
font-size: 26px;
font-weight: 700;
color: #2d3748;
margin-bottom: 8px;
}
.event-time {
font-size: 16px;
color: #667eea;
font-weight: 600;
margin-bottom: 5px;
}
.event-tick {
font-size: 12px;
color: #a0aec0;
font-family: 'Courier New', monospace;
margin-bottom: 10px;
}
.event-encounter {
display: inline-block;
background: linear-gradient(135deg, #f093fb 0%, #f5576c 100%);
color: white;
padding: 6px 18px;
border-radius: 20px;
font-size: 14px;
font-weight: 600;
margin-bottom: 10px;
box-shadow: 0 4px 15px rgba(245, 87, 108, 0.3);
}
.event-activities {
max-width: 800px;
margin: 10px auto 0;
text-align: left;
max-height: 180px;
overflow-y: auto;
}
.activities-title {
font-size: 14px;
font-weight: 600;
color: #2d3748;
margin-bottom: 8px;
text-align: center;
}
.activity-group {
margin-bottom: 8px;
}
.activity-parent {
font-size: 12px;
font-weight: 600;
color: #667eea;
margin-bottom: 4px;
}
.activity-item {
background: white;
padding: 6px 10px;
border-radius: 6px;
margin-bottom: 4px;
border-left: 3px solid #667eea;
font-size: 12px;
color: #4a5568;
}
.procedure-item {
font-size: 11px;
color: #718096;
margin-top: 3px;
padding-left: 10px;
}
.controls-panel {
background: linear-gradient(135deg, #667eea 0%, #764ba2 100%);
border-radius: 12px;
padding: 15px;
color: white;
}
.progress-section {
margin-bottom: 12px;
}
.progress-info {
display: flex;
justify-content: space-between;
margin-bottom: 6px;
font-size: 11px;
opacity: 0.9;
}
.timeline-slider {
width: 100%;
height: 8px;
border-radius: 4px;
background: rgba(255, 255, 255, 0.3);
outline: none;
-webkit-appearance: none;
appearance: none;
cursor: pointer;
}
.timeline-slider::-webkit-slider-thumb {
-webkit-appearance: none;
appearance: none;
width: 20px;
height: 20px;
border-radius: 50%;
background: white;
cursor: pointer;
box-shadow: 0 2px 8px rgba(0,0,0,0.3);
}
.timeline-slider::-moz-range-thumb {
width: 20px;
height: 20px;
border-radius: 50%;
background: white;
cursor: pointer;
border: none;
box-shadow: 0 2px 8px rgba(0,0,0,0.3);
}
.playback-controls {
display: flex;
justify-content: center;
align-items: center;
gap: 10px;
margin-bottom: 12px;
}
.control-btn {
background: rgba(255, 255, 255, 0.2);
border: 2px solid rgba(255, 255, 255, 0.5);
color: white;
width: 40px;
height: 40px;
border-radius: 50%;
display: flex;
align-items: center;
justify-content: center;
cursor: pointer;
transition: all 0.3s ease;
font-size: 16px;
}
.control-btn:hover {
background: rgba(255, 255, 255, 0.3);
transform: scale(1.1);
}
.control-btn:active {
transform: scale(0.95);
}
.control-btn.primary {
width: 48px;
height: 48px;
background: white;
color: #667eea;
font-size: 20px;
}
.control-btn.primary:hover {
background: #f7fafc;
}
.speed-controls {
display: flex;
justify-content: center;
align-items: center;
gap: 8px;
}
.speed-label {
font-size: 11px;
opacity: 0.9;
min-width: 45px;
}
.speed-btn {
background: rgba(255, 255, 255, 0.2);
border: 1px solid rgba(255, 255, 255, 0.3);
color: white;
padding: 4px 10px;
border-radius: 15px;
cursor: pointer;
transition: all 0.2s ease;
font-size: 11px;
font-weight: 600;
}
.speed-btn:hover {
background: rgba(255, 255, 255, 0.3);
}
.speed-btn.active {
background: white;
color: #667eea;
}
.no-events {
text-align: center;
color: #a0aec0;
padding: 60px 20px;
font-size: 18px;
}
.timeline-markers {
display: flex;
justify-content: space-between;
margin-top: 3px;
font-size: 10px;
opacity: 0.7;
}
</style>
</head>
<body>
<div class="main-container">
<!-- Page Header -->
<div class="page-header">
<h1><i class="bi bi-play-circle-fill"></i> Clinical Trial Timeline Player</h1>
<p>Interactive visualization with video-player controls</p>
</div>
<!-- Player Container -->
<div class="player-container">
<!-- Visualization Area -->
<div class="visualization-area">
<div class="timeline-display" id="timeline-display">
<div class="no-events">Load timeline to begin</div>
</div>
</div>
<!-- Controls Panel -->
<div class="controls-panel">
<!-- Progress Section -->
<div class="progress-section">
<div class="progress-info">
<span id="current-time">Event 0 of 0</span>
<span id="duration-time">Duration: --</span>
</div>
<input type="range" class="timeline-slider" id="timeline-slider"
min="0" max="100" value="0" step="1">
<div class="timeline-markers">
<span>Start</span>
<span id="middle-marker">--</span>
<span>End</span>
</div>
</div>
<!-- Playback Controls -->
<div class="playback-controls">
<button class="control-btn" id="first-btn" title="First Event">
<i class="bi bi-skip-start-fill"></i>
</button>
<button class="control-btn" id="prev-btn" title="Previous Event">
<i class="bi bi-chevron-left"></i>
</button>
<button class="control-btn primary" id="play-btn" title="Play/Pause">
<i class="bi bi-play-fill"></i>
</button>
<button class="control-btn" id="next-btn" title="Next Event">
<i class="bi bi-chevron-right"></i>
</button>
<button class="control-btn" id="last-btn" title="Last Event">
<i class="bi bi-skip-end-fill"></i>
</button>
</div>
<!-- Speed Controls -->
<div class="speed-controls">
<span class="speed-label">Speed:</span>
<button class="speed-btn" data-speed="0.5">0.5x</button>
<button class="speed-btn active" data-speed="1">1x</button>
<button class="speed-btn" data-speed="2">2x</button>
<button class="speed-btn" data-speed="5">5x</button>
<button class="speed-btn" data-speed="10">10x</button>
</div>
</div>
</div>
</div>
<!-- Bootstrap 5 JS Bundle -->
<script src="https://cdn.jsdelivr.net/npm/bootstrap@5.3.2/dist/js/bootstrap.bundle.min.js"></script>
<script>
// Data from Python
const data = {
"nodes": [
{
"id": "TP_1",
"tick": -1209600,
"time": "-2 weeks",
"label": "Screen One",
"encounter": "Screening 1",
"activities": {
"items": [
{
"label": "Informed consent",
"parent": "Screening",
"procedures": []
},
{
"label": "Inclusion and exclusion criteria",
"parent": "Screening",
"procedures": []
},
{
"label": "Patient number assigned",
"parent": "Screening",
"procedures": []
},
{
"label": "Demographics",
"parent": "Screening",
"procedures": []
},
{
"label": "Hachinski Ischemic Scale",
"parent": "Safety",
"procedures": []
},
{
"label": "MMSE",
"parent": "Safety",
"procedures": []
},
{
"label": "Physical examination",
"parent": "Safety",
"procedures": []
},
{
"label": "Medical history",
"parent": "Safety",
"procedures": []
},
{
"label": "Habits",
"parent": "Safety",
"procedures": []
},
{
"label": "Chest X-ray",
"parent": "Safety",
"procedures": []
},
{
"label": "Vital Signs and Temperature",
"parent": "Safety",
"procedures": []
},
{
"label": "ECG",
"parent": "Safety",
"procedures": []
},
{
"label": "Placebo TTS test",
"parent": "Safety",
"procedures": []
},
{
"label": "CT scan",
"parent": "Safety",
"procedures": [
"CT Scan"
]
},
{
"label": "Concomitant medications",
"parent": "Safety",
"procedures": []
},
{
"label": "Hematology",
"parent": "Laboratory",
"procedures": []
},
{
"label": "Chemistry",
"parent": "Laboratory",
"procedures": [
"Alanine Aminotransferase Measurement",
"Albumin Measurement",
"Alkaline Phosphatase Measurement",
"Aspartate Aminotransferase Measurement",
"Creatinine Measurement",
"Potassium Measurement",
"Sodium Measurement"
]
},
{
"label": "Uninalysis",
"parent": "Laboratory",
"procedures": []
},
{
"label": "Hemoglobin A1C",
"parent": "Laboratory",
"procedures": []
},
{
"label": "ADAS-Cog",
"parent": "Questionaires",
"procedures": []
},
{
"label": "CIBIC+",
"parent": "Questionaires",
"procedures": []
},
{
"label": "DAD",
"parent": "Questionaires",
"procedures": []
},
{
"label": "NPI-X",
"parent": "Questionaires",
"procedures": []
}
]
},
"edges": []
},
{
"id": "TP_3",
"tick": -1209300,
"time": "-2 weeks, 5 minutes",
"label": "Vital signs supine",
"encounter": null,
"activities": {
"items": [
{
"label": "Vital signs while supine",
"parent": null,
"procedures": [
"Systolic blood pressure",
"Diastolic blood pressure",
"Heart Rate"
]
}
]
},
"edges": []
},
{
"id": "TP_5",
"tick": -1208640,
"time": "-2 weeks, 16 minutes",
"label": "Vital signs after 1 min standing",
"encounter": null,
"activities": {
"items": [
{
"label": "Vital signs while standing",
"parent": null,
"procedures": [
"Systolic blood pressure",
"Diastolic blood pressure",
"Heart Rate"
]
}
]
},
"edges": []
},
{
"id": "TP_7",
"tick": -1207800,
"time": "-2 weeks, 30 minutes",
"label": "Vital signs after 3 min standing",
"encounter": null,
"activities": {
"items": [
{
"label": "Vital signs while standing",
"parent": null,
"procedures": [
"Systolic blood pressure",
"Diastolic blood pressure",
"Heart Rate"
]
}
]
},
"edges": []
},
{
"id": "TP_8",
"tick": -172800,
"time": "-1 weeks, 5 days",
"label": "Screen Two",
"encounter": "Screening 2",
"activities": {
"items": [
{
"label": "Vital Signs and Temperature",
"parent": "Safety",
"procedures": []
},
{
"label": "Ambulatory ECG placed",
"parent": "Safety",
"procedures": []
}
]
},
"edges": []
},
{
"id": "TP_10",
"tick": -172500,
"time": "-1 weeks, 5 days, 5 minutes",
"label": "Vital signs supine",
"encounter": null,
"activities": {
"items": [
{
"label": "Vital signs while supine",
"parent": null,
"procedures": [
"Systolic blood pressure",
"Diastolic blood pressure",
"Heart Rate"
]
}
]
},
"edges": []
},
{
"id": "TP_12",
"tick": -171840,
"time": "-1 weeks, 5 days, 16 minutes",
"label": "Vital signs after 1 min standing",
"encounter": null,
"activities": {
"items": [
{
"label": "Vital signs while standing",
"parent": null,
"procedures": [
"Systolic blood pressure",
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"id": "TP_14",
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{
"label": "Concomitant medications",
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{
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{
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{
"label": "CIBIC+",
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{
"label": "DAD",
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{
"label": "NPI-X",
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"id": "TP_77",
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"id": "TP_79",
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"id": "TP_81",
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"id": "TP_19",
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"label": "Patient Recorded Outcomes",
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"id": "TP_21",
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"id": "TP_23",
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"id": "TP_25",
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{
"label": "Patient Recorded Outcomes",
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}
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},
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"id": "TP_27",
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"time": "6 days",
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{
"label": "Patient Recorded Outcomes",
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"id": "TP_29",
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"id": "TP_31",
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}
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"id": "TP_33",
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"label": "Patient Recorded Outcomes",
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"id": "TP_35",
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{
"label": "Patient Recorded Outcomes",
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