diff --git a/synapse/app/_base.py b/synapse/app/_base.py
index 4cc260d551..bf5bc03565 100644
--- a/synapse/app/_base.py
+++ b/synapse/app/_base.py
@@ -368,6 +368,25 @@ def listen_tcp(
     return r  # type: ignore[return-value]
 
 
+def listen_fd(
+    fd: int,
+    factory: ServerFactory,
+    reactor: IReactorTCP = reactor,
+    backlog: int = 50,
+) -> List[Port]:
+    """
+    Use an inherited file descriptor as a listening socket.
+
+    Returns:
+        list of twisted.internet.tcp.Port listening for TCP connections
+    """
+    sock = socket.socket(fileno=fd)
+    sock.setblocking(False)
+    port = Port._fromListeningDescriptor(reactor, fd, sock.family, factory)
+    port.startListening()
+    return [port]
+
+
 def listen_unix(
     path: str,
     mode: int,
@@ -416,7 +435,15 @@ def listen_http(
     )
 
     if isinstance(listener_config, TCPListenerConfig):
-        if listener_config.is_tls():
+        if listener_config.fd is not None:
+            # Use inherited socket
+            ports = listen_fd(
+                listener_config.fd,
+                site,
+                reactor=reactor,
+            )
+            logger.info("Synapse now listening on inherited fd %d", listener_config.fd)
+        elif listener_config.is_tls():
             # refresh_certificate should have been called before this.
             assert context_factory is not None
             ports = listen_ssl(
diff --git a/synapse/config/server.py b/synapse/config/server.py
index 6b29983617..00b14d00d4 100644
--- a/synapse/config/server.py
+++ b/synapse/config/server.py
@@ -228,11 +228,14 @@ class TCPListenerConfig:
 
     # http_options is only populated if type=http
     http_options: Optional[HttpListenerConfig] = None
+    fd: Optional[int] = attr.ib(default=None, validator=attr.validators.optional(attr.validators.instance_of(int)))
 
     def get_site_tag(self) -> str:
-        """Retrieves http_options.tag if it exists, otherwise the port number."""
+        """Retrieves http_options.tag if it exists, otherwise the port number or fd."""
         if self.http_options and self.http_options.tag is not None:
             return self.http_options.tag
+        elif self.fd is not None:
+            return f"fd{self.fd}"
         else:
             return str(self.port)
 
@@ -970,20 +973,21 @@ def parse_listener_def(num: int, listener: Any) -> ListenerConfig:
 
     port = listener.get("port")
     socket_path = listener.get("path")
-    # Either a port or a path should be declared at a minimum. Using both would be bad.
+    fd = listener.get("fd")
+    # Either a port, fd, or a path should be declared at a minimum. Using more than one would be bad.
     if port is not None and not isinstance(port, int):
         raise ConfigError("Listener configuration is lacking a valid 'port' option")
     if socket_path is not None and not isinstance(socket_path, str):
         raise ConfigError("Listener configuration is lacking a valid 'path' option")
-    if port and socket_path:
+    if fd is not None and not isinstance(fd, int):
+        raise ConfigError("Listener configuration is lacking a valid 'fd' option")
+    if sum(x is not None for x in (port, socket_path, fd)) > 1:
         raise ConfigError(
-            "Can not have both a UNIX socket and an IP/port declared for the same "
-            "resource!"
+            "Can not have more than one of UNIX socket, IP/port, or fd declared for the same resource!"
         )
-    if port is None and socket_path is None:
+    if port is None and socket_path is None and fd is None:
         raise ConfigError(
-            "Must have either a UNIX socket or an IP/port declared for a given "
-            "resource!"
+            "Must have either a UNIX socket, an IP/port, or an fd declared for a given resource!"
         )
 
     tls = listener.get("tls", False)
@@ -1016,6 +1020,10 @@ def parse_listener_def(num: int, listener: Any) -> ListenerConfig:
 
         return UnixListenerConfig(socket_path, socket_mode, listener_type, http_config)
 
+    if fd is not None:
+        assert not tls
+        return TCPListenerConfig(0, [], listener_type, False, http_config, fd=fd)
+
     else:
         assert port is not None
         bind_addresses = listener.get("bind_addresses", [])