diff --git a/packages/injected/src/clock.ts b/packages/injected/src/clock.ts
index c623e0f54f527..18c42e9ced53b 100644
--- a/packages/injected/src/clock.ts
+++ b/packages/injected/src/clock.ts
@@ -612,10 +612,11 @@ function platformOriginals(globalObject: WindowOrWorkerGlobalScope): { raw: Buil
     Date: (globalObject as any).Date,
     performance: globalObject.performance,
     Intl: (globalObject as any).Intl,
+    AbortSignal: (globalObject as any).AbortSignal,
   };
   const bound = { ...raw };
   for (const key of Object.keys(bound) as (keyof Builtins)[]) {
-    if (key !== 'Date' && typeof bound[key] === 'function')
+    if (key !== 'Date' && key !== 'AbortSignal' && typeof bound[key] === 'function')
       bound[key] = (bound[key] as any).bind(globalObject);
   }
   return { raw, bound };
@@ -688,6 +689,7 @@ function createApi(clock: ClockController, originals: Builtins): Builtins {
     Intl: originals.Intl ? createIntl(clock, originals.Intl) : (undefined as unknown as Builtins['Intl']),
     Date: createDate(clock, originals.Date),
     performance: originals.performance ? fakePerformance(clock, originals.performance) : (undefined as unknown as Builtins['performance']),
+    AbortSignal: originals.AbortSignal ? fakeAbortSignal(clock, originals.AbortSignal) : (undefined as unknown as Builtins['AbortSignal']),
   };
 }
 
@@ -715,6 +717,22 @@ function fakePerformance(clock: ClockController, performance: Builtins['performa
   return result;
 }
 
+function fakeAbortSignal(clock: ClockController, abortSignal: Builtins['AbortSignal']): Builtins['AbortSignal'] {
+  const result: any = {
+    ...abortSignal,
+    timeout: (ms: number) => {
+      const controller = new AbortController();
+      clock.addTimer({
+        delay: ms,
+        type: TimerType.Timeout,
+        func: () => controller.abort(new DOMException('This operation was aborted', 'AbortError')),
+      });
+      return controller.signal;
+    },
+  };
+  return result;
+}
+
 export function createClock(globalObject: WindowOrWorkerGlobalScope): { clock: ClockController, api: Builtins, originals: Builtins } {
   const originals = platformOriginals(globalObject);
   const embedder: Embedder = {
@@ -750,6 +768,8 @@ export function install(globalObject: WindowOrWorkerGlobalScope, config: Install
       (globalObject as any).Date = mirrorDateProperties(api.Date, (globalObject as any).Date);
     } else if (method === 'Intl') {
       (globalObject as any).Intl = api[method]!;
+    } else if (method === 'AbortSignal') {
+      (globalObject as any).AbortSignal = api[method]!;
     } else if (method === 'performance') {
       (globalObject as any).performance = api[method]!;
       const kEventTimeStamp = Symbol('playwrightEventTimeStamp');
diff --git a/packages/injected/src/utilityScript.ts b/packages/injected/src/utilityScript.ts
index e61ad96d45b5f..5c54d9ed98814 100644
--- a/packages/injected/src/utilityScript.ts
+++ b/packages/injected/src/utilityScript.ts
@@ -29,6 +29,7 @@ export type Builtins = {
   performance: Window['performance'],
   Intl: typeof window['Intl'],
   Date: typeof window['Date'],
+  AbortSignal: typeof window['AbortSignal'],
 };
 
 export class UtilityScript {
@@ -55,6 +56,7 @@ export class UtilityScript {
         performance: global.performance,
         Intl: global.Intl,
         Date: global.Date,
+        AbortSignal: global.AbortSignal,
       } satisfies Builtins;
     }
     if (this.isUnderTest)
diff --git a/tests/library/page-clock.spec.ts b/tests/library/page-clock.spec.ts
index 277ec4672696a..8fcec7f2ba2ac 100644
--- a/tests/library/page-clock.spec.ts
+++ b/tests/library/page-clock.spec.ts
@@ -534,6 +534,43 @@ it.describe('Date.now', () => {
   });
 });
 
+it('AbortSignal.timeout', { annotation: { type: 'issue', description: 'https://github.com/microsoft/playwright/issues/39293' } }, async ({ page }) => {
+  await page.clock.install({ time: 0 });
+  const controller = await page.evaluateHandle(() => {
+    const signal = AbortSignal.any([
+      AbortSignal.timeout(100)
+    ]);
+    const handle = {
+      signal,
+      event: false,
+      handler: false,
+    };
+    signal.addEventListener('abort', () => handle.event = true);
+    signal.onabort = () => handle.handler = true;
+    return handle;
+  });
+  expect(await controller.evaluate(handle => ({
+    signal: handle.signal.aborted,
+    event: handle.event,
+    handler: handle.handler,
+  }))).toEqual({
+    signal: false,
+    event: false,
+    handler: false,
+  });
+  await page.clock.runFor(200);
+  expect(await controller.evaluate(handle => ({
+    signal: handle.signal.aborted,
+    event: handle.event,
+    handler: handle.handler,
+  }))).toEqual({
+    signal: true,
+    event: true,
+    handler: true,
+  });
+  expect(await page.evaluate(() => AbortSignal.abort().aborted)).toBe(true);
+});
+
 it('correctly increments Date.now()/performance.now() during blocking execution', {
   annotation: {
     type: 'issue',