diff --git a/Misc/NEWS.d/next/Library/2025-12-26-14-51-50.gh-issue-140739.BAbZTo.rst b/Misc/NEWS.d/next/Library/2025-12-26-14-51-50.gh-issue-140739.BAbZTo.rst
new file mode 100644
index 00000000000000..ae93cbb51114f1
--- /dev/null
+++ b/Misc/NEWS.d/next/Library/2025-12-26-14-51-50.gh-issue-140739.BAbZTo.rst
@@ -0,0 +1,2 @@
+Fix several crashes due to reading invalid memory in the new Tachyon
+sampling profiler. Patch by Pablo Galindo.
diff --git a/Modules/_remote_debugging/_remote_debugging.h b/Modules/_remote_debugging/_remote_debugging.h
index 4119d916be7a63..78add74423b608 100644
--- a/Modules/_remote_debugging/_remote_debugging.h
+++ b/Modules/_remote_debugging/_remote_debugging.h
@@ -140,6 +140,11 @@ typedef enum _WIN32_THREADSTATE {
 #define SIZEOF_GC_RUNTIME_STATE sizeof(struct _gc_runtime_state)
 #define SIZEOF_INTERPRETER_STATE sizeof(PyInterpreterState)
 
+/* Maximum sizes for validation to prevent buffer overflows from corrupted data */
+#define MAX_STACK_CHUNK_SIZE (16 * 1024 * 1024)  /* 16 MB max for stack chunks */
+#define MAX_LONG_DIGITS 64  /* Allows values up to ~2^1920 */
+#define MAX_SET_TABLE_SIZE (1 << 20)  /* 1 million entries max for set iteration */
+
 #ifndef MAX
 #define MAX(a, b) ((a) > (b) ? (a) : (b))
 #endif
@@ -451,6 +456,7 @@ extern PyObject *make_frame_info(
 extern bool parse_linetable(
     const uintptr_t addrq,
     const char* linetable,
+    Py_ssize_t linetable_size,
     int firstlineno,
     LocationInfo* info
 );
diff --git a/Modules/_remote_debugging/asyncio.c b/Modules/_remote_debugging/asyncio.c
index 7f91f16e3a2ce6..3fcc939fd0e876 100644
--- a/Modules/_remote_debugging/asyncio.c
+++ b/Modules/_remote_debugging/asyncio.c
@@ -112,9 +112,17 @@ iterate_set_entries(
     }
 
     Py_ssize_t num_els = GET_MEMBER(Py_ssize_t, set_object, unwinder->debug_offsets.set_object.used);
-    Py_ssize_t set_len = GET_MEMBER(Py_ssize_t, set_object, unwinder->debug_offsets.set_object.mask) + 1;
+    Py_ssize_t mask = GET_MEMBER(Py_ssize_t, set_object, unwinder->debug_offsets.set_object.mask);
     uintptr_t table_ptr = GET_MEMBER(uintptr_t, set_object, unwinder->debug_offsets.set_object.table);
 
+    // Validate mask and num_els to prevent huge loop iterations from garbage data
+    if (mask < 0 || mask >= MAX_SET_TABLE_SIZE || num_els < 0 || num_els > mask + 1) {
+        set_exception_cause(unwinder, PyExc_RuntimeError,
+            "Invalid set object (corrupted remote memory)");
+        return -1;
+    }
+    Py_ssize_t set_len = mask + 1;
+
     Py_ssize_t i = 0;
     Py_ssize_t els = 0;
     while (i < set_len && els < num_els) {
@@ -812,14 +820,15 @@ append_awaited_by_for_thread(
             return -1;
         }
 
-        if (GET_MEMBER(uintptr_t, task_node, unwinder->debug_offsets.llist_node.next) == 0) {
+        uintptr_t next_node = GET_MEMBER(uintptr_t, task_node, unwinder->debug_offsets.llist_node.next);
+        if (next_node == 0) {
             PyErr_SetString(PyExc_RuntimeError,
                            "Invalid linked list structure reading remote memory");
             set_exception_cause(unwinder, PyExc_RuntimeError, "NULL pointer in task linked list");
             return -1;
         }
 
-        uintptr_t task_addr = (uintptr_t)GET_MEMBER(uintptr_t, task_node, unwinder->debug_offsets.llist_node.next)
+        uintptr_t task_addr = next_node
             - (uintptr_t)unwinder->async_debug_offsets.asyncio_task_object.task_node;
 
         if (process_single_task_node(unwinder, task_addr, NULL, result) < 0) {
@@ -830,7 +839,7 @@ append_awaited_by_for_thread(
         // Read next node
         if (_Py_RemoteDebug_PagedReadRemoteMemory(
                 &unwinder->handle,
-                (uintptr_t)GET_MEMBER(uintptr_t, task_node, unwinder->debug_offsets.llist_node.next),
+                next_node,
                 sizeof(task_node),
                 task_node) < 0) {
             set_exception_cause(unwinder, PyExc_RuntimeError, "Failed to read next task node in awaited_by");
diff --git a/Modules/_remote_debugging/code_objects.c b/Modules/_remote_debugging/code_objects.c
index ca6ffe7a00af60..9b7b4dc22b873b 100644
--- a/Modules/_remote_debugging/code_objects.c
+++ b/Modules/_remote_debugging/code_objects.c
@@ -123,44 +123,74 @@ cache_tlbc_array(RemoteUnwinderObject *unwinder, uintptr_t code_addr, uintptr_t
  * LINE TABLE PARSING FUNCTIONS
  * ============================================================================ */
 
+// Inline helper for bounds-checked byte reading (no function call overhead)
+static inline int
+read_byte(const uint8_t **ptr, const uint8_t *end, uint8_t *out)
+{
+    if (*ptr >= end) {
+        return -1;
+    }
+    *out = *(*ptr)++;
+    return 0;
+}
+
 static int
-scan_varint(const uint8_t **ptr)
+scan_varint(const uint8_t **ptr, const uint8_t *end)
 {
-    unsigned int read = **ptr;
-    *ptr = *ptr + 1;
+    uint8_t read;
+    if (read_byte(ptr, end, &read) < 0) {
+        return -1;
+    }
     unsigned int val = read & 63;
     unsigned int shift = 0;
     while (read & 64) {
-        read = **ptr;
-        *ptr = *ptr + 1;
+        if (read_byte(ptr, end, &read) < 0) {
+            return -1;
+        }
         shift += 6;
+        // Prevent infinite loop on malformed data (shift overflow)
+        if (shift > 28) {
+            return -1;
+        }
         val |= (read & 63) << shift;
     }
-    return val;
+    return (int)val;
 }
 
 static int
-scan_signed_varint(const uint8_t **ptr)
+scan_signed_varint(const uint8_t **ptr, const uint8_t *end)
 {
-    unsigned int uval = scan_varint(ptr);
+    int uval = scan_varint(ptr, end);
+    if (uval < 0) {
+        return INT_MIN;  // Error sentinel (valid signed varints won't be INT_MIN)
+    }
     if (uval & 1) {
-        return -(int)(uval >> 1);
+        return -(int)((unsigned int)uval >> 1);
     }
     else {
-        return uval >> 1;
+        return (int)((unsigned int)uval >> 1);
     }
 }
 
 bool
-parse_linetable(const uintptr_t addrq, const char* linetable, int firstlineno, LocationInfo* info)
+parse_linetable(const uintptr_t addrq, const char* linetable, Py_ssize_t linetable_size,
+                int firstlineno, LocationInfo* info)
 {
+    // Reject garbage: zero or negative size
+    if (linetable_size <= 0) {
+        return false;
+    }
+
     const uint8_t* ptr = (const uint8_t*)(linetable);
+    const uint8_t* end = ptr + linetable_size;
     uintptr_t addr = 0;
     int computed_line = firstlineno;  // Running accumulator, separate from output
+    int val;  // Temporary for varint results
+    uint8_t byte;  // Temporary for byte reads
     const size_t MAX_LINETABLE_ENTRIES = 65536;
     size_t entry_count = 0;
 
-    while (*ptr != '\0' && entry_count < MAX_LINETABLE_ENTRIES) {
+    while (ptr < end && *ptr != '\0' && entry_count < MAX_LINETABLE_ENTRIES) {
         entry_count++;
         uint8_t first_byte = *(ptr++);
         uint8_t code = (first_byte >> 3) & 15;
@@ -173,14 +203,34 @@ parse_linetable(const uintptr_t addrq, const char* linetable, int firstlineno, L
                 info->column = info->end_column = -1;
                 break;
             case PY_CODE_LOCATION_INFO_LONG:
-                computed_line += scan_signed_varint(&ptr);
+                val = scan_signed_varint(&ptr, end);
+                if (val == INT_MIN) {
+                    return false;
+                }
+                computed_line += val;
                 info->lineno = computed_line;
-                info->end_lineno = computed_line + scan_varint(&ptr);
-                info->column = scan_varint(&ptr) - 1;
-                info->end_column = scan_varint(&ptr) - 1;
+                val = scan_varint(&ptr, end);
+                if (val < 0) {
+                    return false;
+                }
+                info->end_lineno = computed_line + val;
+                val = scan_varint(&ptr, end);
+                if (val < 0) {
+                    return false;
+                }
+                info->column = val - 1;
+                val = scan_varint(&ptr, end);
+                if (val < 0) {
+                    return false;
+                }
+                info->end_column = val - 1;
                 break;
             case PY_CODE_LOCATION_INFO_NO_COLUMNS:
-                computed_line += scan_signed_varint(&ptr);
+                val = scan_signed_varint(&ptr, end);
+                if (val == INT_MIN) {
+                    return false;
+                }
+                computed_line += val;
                 info->lineno = info->end_lineno = computed_line;
                 info->column = info->end_column = -1;
                 break;
@@ -189,17 +239,25 @@ parse_linetable(const uintptr_t addrq, const char* linetable, int firstlineno, L
             case PY_CODE_LOCATION_INFO_ONE_LINE2:
                 computed_line += code - 10;
                 info->lineno = info->end_lineno = computed_line;
-                info->column = *(ptr++);
-                info->end_column = *(ptr++);
+                if (read_byte(&ptr, end, &byte) < 0) {
+                    return false;
+                }
+                info->column = byte;
+                if (read_byte(&ptr, end, &byte) < 0) {
+                    return false;
+                }
+                info->end_column = byte;
                 break;
             default: {
-                uint8_t second_byte = *(ptr++);
-                if ((second_byte & 128) != 0) {
+                if (read_byte(&ptr, end, &byte) < 0) {
+                    return false;
+                }
+                if ((byte & 128) != 0) {
                     return false;
                 }
                 info->lineno = info->end_lineno = computed_line;
-                info->column = code << 3 | (second_byte >> 4);
-                info->end_column = info->column + (second_byte & 15);
+                info->column = code << 3 | (byte >> 4);
+                info->end_column = info->column + (byte & 15);
                 break;
             }
         }
@@ -384,8 +442,14 @@ parse_code_object(RemoteUnwinderObject *unwinder,
         tlbc_entry = get_tlbc_cache_entry(unwinder, real_address, unwinder->tlbc_generation);
     }
 
-    if (tlbc_entry && ctx->tlbc_index < tlbc_entry->tlbc_array_size) {
-        assert(ctx->tlbc_index >= 0);
+    // Validate tlbc_index and check TLBC cache
+    if (tlbc_entry) {
+        // Validate index bounds (also catches negative values since tlbc_index is signed)
+        if (ctx->tlbc_index < 0 || ctx->tlbc_index >= tlbc_entry->tlbc_array_size) {
+            set_exception_cause(unwinder, PyExc_RuntimeError,
+                "Invalid tlbc_index (corrupted remote memory)");
+            goto error;
+        }
         assert(tlbc_entry->tlbc_array_size > 0);
         // Use cached TLBC data
         uintptr_t *entries = (uintptr_t *)((char *)tlbc_entry->tlbc_array + sizeof(Py_ssize_t));
@@ -398,7 +462,7 @@ parse_code_object(RemoteUnwinderObject *unwinder,
         }
     }
 
-    // Fall back to main bytecode
+    // Fall back to main bytecode (no tlbc_entry or tlbc_bytecode_addr was 0)
     addrq = (uint16_t *)ip - (uint16_t *)meta->addr_code_adaptive;
 
 done_tlbc:
@@ -409,6 +473,7 @@ parse_code_object(RemoteUnwinderObject *unwinder,
     ;  // Empty statement to avoid C23 extension warning
     LocationInfo info = {0};
     bool ok = parse_linetable(addrq, PyBytes_AS_STRING(meta->linetable),
+                              PyBytes_GET_SIZE(meta->linetable),
                               meta->first_lineno, &info);
     if (!ok) {
         info.lineno = -1;
diff --git a/Modules/_remote_debugging/frames.c b/Modules/_remote_debugging/frames.c
index d9fece6459875a..02c48205b85a37 100644
--- a/Modules/_remote_debugging/frames.c
+++ b/Modules/_remote_debugging/frames.c
@@ -45,6 +45,15 @@ process_single_stack_chunk(
     // Check actual size and reread if necessary
     size_t actual_size = GET_MEMBER(size_t, this_chunk, offsetof(_PyStackChunk, size));
     if (actual_size != current_size) {
+        // Validate size: reject garbage (too small or unreasonably large)
+        // Size must be at least enough for the header and reasonably bounded
+        if (actual_size <= offsetof(_PyStackChunk, data) || actual_size > MAX_STACK_CHUNK_SIZE) {
+            PyMem_RawFree(this_chunk);
+            set_exception_cause(unwinder, PyExc_RuntimeError,
+                "Invalid stack chunk size (corrupted remote memory)");
+            return -1;
+        }
+
         this_chunk = PyMem_RawRealloc(this_chunk, actual_size);
         if (!this_chunk) {
             PyErr_NoMemory();
@@ -129,7 +138,11 @@ void *
 find_frame_in_chunks(StackChunkList *chunks, uintptr_t remote_ptr)
 {
     for (size_t i = 0; i < chunks->count; ++i) {
-        assert(chunks->chunks[i].size > offsetof(_PyStackChunk, data));
+        // Validate size: reject garbage that would cause underflow
+        if (chunks->chunks[i].size <= offsetof(_PyStackChunk, data)) {
+            // Skip this chunk - corrupted size from remote memory
+            continue;
+        }
         uintptr_t base = chunks->chunks[i].remote_addr + offsetof(_PyStackChunk, data);
         size_t payload = chunks->chunks[i].size - offsetof(_PyStackChunk, data);
 
diff --git a/Modules/_remote_debugging/module.c b/Modules/_remote_debugging/module.c
index e14a23357fb400..737787a331f948 100644
--- a/Modules/_remote_debugging/module.c
+++ b/Modules/_remote_debugging/module.c
@@ -584,6 +584,7 @@ _remote_debugging_RemoteUnwinder_get_stack_trace_impl(RemoteUnwinderObject *self
         }
 
         while (current_tstate != 0) {
+            uintptr_t prev_tstate = current_tstate;
             PyObject* frame_info = unwind_stack_for_thread(self, &current_tstate,
                                                            gil_holder_tstate,
                                                            gc_frame);
@@ -591,6 +592,14 @@ _remote_debugging_RemoteUnwinder_get_stack_trace_impl(RemoteUnwinderObject *self
                 // Check if this was an intentional skip due to mode-based filtering
                 if ((self->mode == PROFILING_MODE_CPU || self->mode == PROFILING_MODE_GIL ||
                      self->mode == PROFILING_MODE_EXCEPTION) && !PyErr_Occurred()) {
+                    // Detect cycle: if current_tstate didn't advance, we have corrupted data
+                    if (current_tstate == prev_tstate) {
+                        Py_DECREF(interpreter_threads);
+                        set_exception_cause(self, PyExc_RuntimeError,
+                            "Thread list cycle detected (corrupted remote memory)");
+                        Py_CLEAR(result);
+                        goto exit;
+                    }
                     // Thread was skipped due to mode filtering, continue to next thread
                     continue;
                 }
diff --git a/Modules/_remote_debugging/object_reading.c b/Modules/_remote_debugging/object_reading.c
index 2f465ca0cac41d..447b7fd5926064 100644
--- a/Modules/_remote_debugging/object_reading.c
+++ b/Modules/_remote_debugging/object_reading.c
@@ -194,9 +194,21 @@ read_py_long(
         return 0;
     }
 
-    // If the long object has inline digits, use them directly
+    // Validate size: reject garbage (negative or unreasonably large)
+    if (size < 0 || size > MAX_LONG_DIGITS) {
+        set_exception_cause(unwinder, PyExc_RuntimeError,
+            "Invalid PyLong size (corrupted remote memory)");
+        return -1;
+    }
+
+    // Calculate how many digits fit inline in our local buffer
+    Py_ssize_t ob_digit_offset = unwinder->debug_offsets.long_object.ob_digit;
+    Py_ssize_t inline_digits_space = SIZEOF_LONG_OBJ - ob_digit_offset;
+    Py_ssize_t max_inline_digits = inline_digits_space / (Py_ssize_t)sizeof(digit);
+
+    // If the long object has inline digits that fit in our buffer, use them directly
     digit *digits;
-    if (size <= _PY_NSMALLNEGINTS + _PY_NSMALLPOSINTS) {
+    if (size <= max_inline_digits && size <= _PY_NSMALLNEGINTS + _PY_NSMALLPOSINTS) {
         // For small integers, digits are inline in the long_value.ob_digit array
         digits = (digit *)PyMem_RawMalloc(size * sizeof(digit));
         if (!digits) {
@@ -204,7 +216,7 @@ read_py_long(
             set_exception_cause(unwinder, PyExc_MemoryError, "Failed to allocate digits for small PyLong");
             return -1;
         }
-        memcpy(digits, long_obj + unwinder->debug_offsets.long_object.ob_digit, size * sizeof(digit));
+        memcpy(digits, long_obj + ob_digit_offset, size * sizeof(digit));
     } else {
         // For larger integers, we need to read the digits separately
         digits = (digit *)PyMem_RawMalloc(size * sizeof(digit));