condition variant list

[cindywen96]

Regarding the conditional mode of remeta gene, would it be possible to add a feature for remeta to automatically identify common variant signals to condition on? The buffer LD matrices and single-variant summary statistics are already available as inputs, which should be sufficient to run fine-mapping like susie or simple distance-based clumping internally to select conditioning variants.

This would be especially useful for custom traits where no published GWAS index SNPs exist. Ideally both options could be supported: (1) input a user-defined list of condition variants (2) let remeta internally select condition variants.

Thanks!