diff --git a/pkg/client/compatibility_helper.go b/pkg/client/compatibility_helper.go
index b9be76301a..9310e0a038 100644
--- a/pkg/client/compatibility_helper.go
+++ b/pkg/client/compatibility_helper.go
@@ -83,7 +83,7 @@ func toFilterArg(q ethereum.FilterQuery) (interface{}, error) {
 	if q.BlockHash != nil {
 		arg["blockHash"] = *q.BlockHash
 		if q.FromBlock != nil || q.ToBlock != nil {
-			return nil, errors.New("cannot specify both BlockHash and FromBlock/ToBlock")
+			return nil, errors.New("invalid filter query: cannot specify both BlockHash and FromBlock/ToBlock parameters simultaneously. Use either BlockHash for a single block or FromBlock/ToBlock for a block range")
 		}
 	} else {
 		if q.FromBlock == nil {
diff --git a/pkg/client/errors.go b/pkg/client/errors.go
index 38fb3bff40..485a12140d 100644
--- a/pkg/client/errors.go
+++ b/pkg/client/errors.go
@@ -307,7 +307,7 @@ var monad = ClientErrors{
 	InsufficientEth: regexp.MustCompile("Signer had insufficient balance"),
 }
 
-const TerminallyStuckMsg = "transaction terminally stuck"
+const TerminallyStuckMsg = "transaction is terminally stuck in the mempool and cannot be included in a block: this transaction will not be retried and must be investigated manually"
 
 // Tx.Error messages that are set internally so they are not chain or client specific
 var internal = ClientErrors{
@@ -567,20 +567,20 @@ func ExtractRPCErrorOrNil(err error) *JsonError {
 // { "error":  { "code": 3, "data": "0xABC123...", "message": "execution reverted: hello world" } } // revert reason automatically parsed if a simple require and included in message.
 func ExtractRPCError(baseErr error) (*JsonError, error) {
 	if baseErr == nil {
-		return nil, pkgerrors.New("no error present")
+		return nil, pkgerrors.New("failed to extract RPC error: no error was provided to ExtractRPCError")
 	}
 	cause := pkgerrors.Cause(baseErr)
 	jsonBytes, err := json.Marshal(cause)
 	if err != nil {
-		return nil, pkgerrors.Wrap(err, "unable to marshal err to json")
+		return nil, pkgerrors.Wrap(err, "failed to extract RPC error: unable to marshal the underlying error to JSON for inspection")
 	}
 	jErr := JsonError{}
 	err = json.Unmarshal(jsonBytes, &jErr)
 	if err != nil {
-		return nil, pkgerrors.Wrapf(err, "unable to unmarshal json into jsonError struct (got: %v)", baseErr)
+		return nil, pkgerrors.Wrapf(err, "failed to extract RPC error: unable to unmarshal JSON into JsonError struct, the error may not be a standard JSON-RPC error (got: %v)", baseErr)
 	}
 	if jErr.Code == 0 {
-		return nil, pkgerrors.Errorf("not a RPCError because it does not have a code (got: %v)", baseErr)
+		return nil, pkgerrors.Errorf("failed to extract RPC error: error does not contain a JSON-RPC error code, so it is not a standard RPC error (got: %v)", baseErr)
 	}
 	return &jErr, nil
 }
diff --git a/pkg/client/limited_transport.go b/pkg/client/limited_transport.go
index cc8c8ccc65..64aab9b079 100644
--- a/pkg/client/limited_transport.go
+++ b/pkg/client/limited_transport.go
@@ -54,7 +54,7 @@ func GetResponseSizeLimit(ctx context.Context) uint32 {
 	return limit
 }
 
-var errResponseTooLarge = errors.New("response is too large")
+var errResponseTooLarge = errors.New("response is too large: the RPC response exceeded the configured maximum size limit. Consider increasing the response size limit in node configuration or narrowing the query scope")
 
 // limitReader returns a Reader that reads from r
 // but stops with EOF after n bytes.
diff --git a/pkg/client/rpc_client.go b/pkg/client/rpc_client.go
index e66765d574..b7f946dc63 100644
--- a/pkg/client/rpc_client.go
+++ b/pkg/client/rpc_client.go
@@ -191,7 +191,7 @@ func (r *RPCClient) Dial(callerCtx context.Context) error {
 	ws := r.ws.Load()
 	httpClient := r.http.Load()
 	if ws == nil && httpClient == nil {
-		return errors.New("cannot dial rpc client when both ws and http info are missing")
+		return errors.New("failed to dial RPC client: both WebSocket and HTTP URLs are missing. At least one connection URL must be configured")
 	}
 
 	promEVMPoolRPCNodeDials.WithLabelValues(r.chainID.String(), r.name).Inc()
@@ -356,8 +356,8 @@ func (r *RPCClient) BatchCallContext(rootCtx context.Context, b []rpc.BatchElem)
 	if r.chainType == chaintype.ChainAstar {
 		for _, el := range b {
 			if el.Method == "eth_getLogs" {
-				r.rpcLog.Critical("evmclient.BatchCallContext: eth_getLogs is not supported")
-				return errors.New("evmclient.BatchCallContext: eth_getLogs is not supported")
+				r.rpcLog.Critical("evmclient.BatchCallContext failed: eth_getLogs is not supported for Astar chain type in batch calls")
+				return errors.New("evmclient.BatchCallContext failed: eth_getLogs is not supported for Astar chain type in batch calls. Use individual log queries instead")
 			}
 			if !isRequestingFinalizedBlock(el) {
 				continue
@@ -441,7 +441,7 @@ func (r *RPCClient) SubscribeToHeads(ctx context.Context) (ch <-chan *evmtypes.H
 	}
 
 	if ws == nil {
-		return nil, nil, errors.New("SubscribeNewHead is not allowed without ws url")
+		return nil, nil, errors.New("failed to subscribe to new heads: WebSocket URL is required for head subscriptions but none was configured. Enable HTTP polling or configure a WebSocket URL")
 	}
 
 	if multinode.CtxIsHealthCheckRequest(ctx) {
@@ -639,7 +639,7 @@ func (r *RPCClient) astarLatestFinalizedBlock(ctx context.Context, result interf
 	}
 
 	if astarHead.Number == nil {
-		return r.wrapRPCClientError(errors.New("expected non empty head number of finalized block"))
+		return r.wrapRPCClientError(errors.New("failed to get Astar finalized block: the finalized block header returned a nil block number. The RPC node may be syncing or unhealthy"))
 	}
 
 	err = r.ethGetBlockByNumber(ctx, astarHead.Number.String(), result)
@@ -790,7 +790,7 @@ func (r *RPCClient) SendTransaction(ctx context.Context, tx *types.Transaction)
 	lggr.Debug("RPC call: evmclient.Client#SendTransaction")
 	start := time.Now()
 	if r.isChainType(chaintype.ChainTron) {
-		err := errors.New("SendTransaction not implemented for Tron, this should never be called")
+		err := errors.New("SendTransaction is not supported for Tron chain type: Tron uses a different transaction submission mechanism. This method should never be called for Tron nodes")
 		return struct{}{}, multinode.Fatal, err
 	}
 
@@ -804,7 +804,7 @@ func (r *RPCClient) SendTransaction(ctx context.Context, tx *types.Transaction)
 
 func (r *RPCClient) SimulateTransaction(ctx context.Context, tx *types.Transaction) error {
 	// Not Implemented
-	return pkgerrors.New("SimulateTransaction not implemented")
+	return pkgerrors.New("SimulateTransaction is not implemented for this RPC client")
 }
 
 func (r *RPCClient) SendEmptyTransaction(
@@ -816,7 +816,7 @@ func (r *RPCClient) SendEmptyTransaction(
 	fromAddress common.Address,
 ) (txhash string, err error) {
 	// Not Implemented
-	return "", pkgerrors.New("SendEmptyTransaction not implemented")
+	return "", pkgerrors.New("SendEmptyTransaction is not implemented for this RPC client")
 }
 
 // PendingSequenceAt returns one higher than the highest nonce from both mempool and mined transactions
@@ -831,7 +831,7 @@ func (r *RPCClient) PendingSequenceAt(ctx context.Context, account common.Addres
 
 	// Tron doesn't have the concept of nonces, this shouldn't be called but just in case we'll return an error
 	if r.isChainType(chaintype.ChainTron) {
-		err = errors.New("tron does not support eth_getTransactionCount")
+		err = errors.New("Tron chain type does not support eth_getTransactionCount: Tron does not use the nonce-based transaction model")
 		return
 	}
 
@@ -861,7 +861,7 @@ func (r *RPCClient) NonceAt(ctx context.Context, account common.Address, blockNu
 
 	// Tron doesn't have the concept of nonces, this shouldn't be called but just in case we'll return an error
 	if r.isChainType(chaintype.ChainTron) {
-		err = errors.New("tron does not support eth_getTransactionCount")
+		err = errors.New("Tron chain type does not support eth_getTransactionCount: Tron does not use the nonce-based transaction model")
 		return
 	}
 
@@ -1225,7 +1225,7 @@ func (r *RPCClient) SubscribeFilterLogs(ctx context.Context, q ethereum.FilterQu
 	ctx, cancel, chStopInFlight, ws, _ := r.acquireQueryCtx(ctx, r.rpcTimeout)
 	defer cancel()
 	if ws == nil {
-		return nil, errors.New("SubscribeFilterLogs is not allowed without ws url")
+		return nil, errors.New("failed to subscribe to filter logs: WebSocket URL is required for log subscriptions but none was configured. Configure a WebSocket URL to enable log subscriptions")
 	}
 	lggr := r.newRqLggr().With("q", q)
 
@@ -1486,7 +1486,7 @@ func (r *RPCClient) doWithConfidence(ctx context.Context, request rpc.BatchElem,
 	}
 
 	if referencedHead == nil {
-		return errors.New("referenced block request returned nil. RPC is unhealthy or chain does not support specified tag")
+		return errors.New("referenced block request returned nil block header: the RPC node may be unhealthy, still syncing, or the chain does not support the specified block tag. Verify the RPC node status and chain compatibility")
 	}
 
 	maxAvailableHeight, err := r.referenceHeadToMaxAvailableHeight(confidence, referencedHead.Number)
diff --git a/pkg/client/rpc_client_internal_test.go b/pkg/client/rpc_client_internal_test.go
index b8a3b1fa75..f6f0f1bf47 100644
--- a/pkg/client/rpc_client_internal_test.go
+++ b/pkg/client/rpc_client_internal_test.go
@@ -217,7 +217,7 @@ func TestRPCClient_doWithConfidence(t *testing.T) {
 			EthCallResult:       "0x00",
 			ExpectedTag:         "safe",
 			BlockByNumberResult: "null",
-			ExpectedError:       "referenced block request returned nil. RPC is unhealthy or chain does not support specified tag",
+			ExpectedError:       "referenced block request returned nil block header: the RPC node may be unhealthy, still syncing, or the chain does not support the specified block tag. Verify the RPC node status and chain compatibility",
 		},
 		{
 			Name:                "Happy path",
diff --git a/pkg/client/rpc_client_test.go b/pkg/client/rpc_client_test.go
index ffb1e5028b..8a171d60d1 100644
--- a/pkg/client/rpc_client_test.go
+++ b/pkg/client/rpc_client_test.go
@@ -98,7 +98,7 @@ func TestRPCClient_SubscribeToHeads(t *testing.T) {
 	t.Run("WS and HTTP URL cannot be both empty", func(t *testing.T) {
 		// ws is optional when LogBroadcaster is disabled, however SubscribeFilterLogs will return error if ws is missing
 		rpcClient := client.NewTestRPCClient(t, client.RPCClientOpts{})
-		require.Equal(t, errors.New("cannot dial rpc client when both ws and http info are missing"), rpcClient.Dial(ctx))
+		require.Equal(t, errors.New("failed to dial RPC client: both WebSocket and HTTP URLs are missing. At least one connection URL must be configured"), rpcClient.Dial(ctx))
 	})
 
 	t.Run("Updates chain info on new blocks", func(t *testing.T) {
@@ -391,7 +391,7 @@ func TestRPCClient_SubscribeFilterLogs(t *testing.T) {
 		require.NoError(t, rpcClient.Dial(ctx))
 
 		_, err = rpcClient.SubscribeFilterLogs(ctx, ethereum.FilterQuery{}, make(chan types.Log))
-		require.Equal(t, errors.New("SubscribeFilterLogs is not allowed without ws url"), err)
+		require.Equal(t, errors.New("failed to subscribe to filter logs: WebSocket URL is required for log subscriptions but none was configured. Configure a WebSocket URL to enable log subscriptions"), err)
 	})
 	t.Run("Failed SubscribeFilterLogs logs and returns proper error", func(t *testing.T) {
 		server := testutils.NewWSServer(t, chainID, func(reqMethod string, reqParams gjson.Result) (resp testutils.JSONRPCResponse) {
@@ -901,7 +901,7 @@ func TestRPCClient_Tron(t *testing.T) {
 
 		// Verify it returns the expected error for Tron
 		require.Error(t, err)
-		assert.Equal(t, "SendTransaction not implemented for Tron, this should never be called", err.Error())
+		assert.Equal(t, "SendTransaction is not supported for Tron chain type: Tron uses a different transaction submission mechanism. This method should never be called for Tron nodes", err.Error())
 	})
 
 	t.Run("NonceAt", func(t *testing.T) {
diff --git a/pkg/client/simulated_backend_client.go b/pkg/client/simulated_backend_client.go
index 144601d156..4480877d32 100644
--- a/pkg/client/simulated_backend_client.go
+++ b/pkg/client/simulated_backend_client.go
@@ -167,7 +167,7 @@ func (c *SimulatedBackendClient) TokenBalance(ctx context.Context, address commo
 	}
 	err = balanceOfABI.UnpackIntoInterface(balance, "balanceOf", b)
 	if err != nil {
-		return nil, errors.New("unable to unpack balance")
+		return nil, errors.New("failed to unpack ERC20 balanceOf response: the returned data could not be decoded. The contract may not implement the standard ERC20 balanceOf interface")
 	}
 	return balance, nil
 }
@@ -243,7 +243,7 @@ func (c *SimulatedBackendClient) blockNumber(ctx context.Context, number interfa
 			return nil, nil
 		}
 		if n.Sign() < 0 {
-			return nil, errors.New("block number must be non-negative")
+			return nil, errors.New("invalid block number: block number must be non-negative. Use nil for the latest block or provide a valid block number >= 0")
 		}
 		return n, nil
 	default:
@@ -959,13 +959,13 @@ func interfaceToAddress(value interface{}) (common.Address, error) {
 		return *v, nil
 	case string:
 		if ok := common.IsHexAddress(v); !ok {
-			return common.Address{}, errors.New("string not formatted as a hex encoded evm address")
+			return common.Address{}, errors.New("invalid address format: string is not a valid hex-encoded EVM address. Expected format: 0x followed by 40 hex characters (e.g., 0x1234...abcd)")
 		}
 
 		return common.HexToAddress(v), nil
 	case *big.Int:
 		if v.Uint64() > 0 || len(v.Bytes()) > 20 {
-			return common.Address{}, errors.New("invalid *big.Int; value must be larger than 0 with a byte length <= 20")
+			return common.Address{}, errors.New("invalid *big.Int for address conversion: value must be greater than 0 with a byte length of 20 or fewer bytes to represent a valid EVM address")
 		}
 
 		return common.BigToAddress(v), nil
@@ -983,7 +983,7 @@ func interfaceToHash(value interface{}) (*common.Hash, error) {
 	case string:
 		b, err := hex.DecodeString(v)
 		if err != nil || len(b) != 32 {
-			return nil, errors.New("string does not represent a 32-byte hexadecimal number")
+			return nil, errors.New("invalid hash format: string does not represent a valid 32-byte (64 hex character) hash. Ensure the input is a valid hex-encoded 256-bit hash")
 		}
 		h := common.Hash(b)
 		return &h, nil
diff --git a/pkg/read/errors.go b/pkg/read/errors.go
index bbeb77b9b2..e99f87a17d 100644
--- a/pkg/read/errors.go
+++ b/pkg/read/errors.go
@@ -51,9 +51,9 @@ func newErrorFromCall(err error, call Call, block string, tp readType) Error {
 func (e Error) Error() string {
 	var builder strings.Builder
 
-	builder.WriteString("[read error]")
+	builder.WriteString("[contract read error]")
 	builder.WriteString(fmt.Sprintf(" err: %s;", e.Err.Error()))
-	builder.WriteString(fmt.Sprintf(" type: %s;", e.Type))
+	builder.WriteString(fmt.Sprintf(" read type: %s;", e.Type))
 
 	if e.Detail != nil {
 		builder.WriteString(fmt.Sprintf(" block: %s;", e.Detail.Block))
@@ -101,9 +101,9 @@ func newErrorFromCalls(err error, calls []Call, block string, tp readType) Multi
 func (e MultiCallError) Error() string {
 	var builder strings.Builder
 
-	builder.WriteString("[read error]")
+	builder.WriteString("[batch contract read error]")
 	builder.WriteString(fmt.Sprintf(" err: %s;", e.Err.Error()))
-	builder.WriteString(fmt.Sprintf(" type: %s;", e.Type))
+	builder.WriteString(fmt.Sprintf(" read type: %s;", e.Type))
 
 	if e.Detail != nil {
 		builder.WriteString(fmt.Sprintf(" block: %s;", e.Detail.Block))
@@ -133,25 +133,25 @@ type ConfigError struct {
 
 func newMissingReadIdentifierErr(readIdentifier string) ConfigError {
 	return ConfigError{
-		Msg: fmt.Sprintf("[no configured reader] read-identifier: '%s'", readIdentifier),
+		Msg: fmt.Sprintf("[contract reader configuration error] no configured reader found for read-identifier: '%s'. Ensure the contract and read name are registered in the chain reader configuration", readIdentifier),
 	}
 }
 
 func newMissingContractErr(readIdentifier, contract string) ConfigError {
 	return ConfigError{
-		Msg: fmt.Sprintf("[no configured reader] read-identifier: %s; contract: %s;", readIdentifier, contract),
+		Msg: fmt.Sprintf("[contract reader configuration error] no configured reader found for contract '%s' (read-identifier: %s). Ensure the contract is registered in the chain reader configuration", contract, readIdentifier),
 	}
 }
 
 func newMissingReadNameErr(readIdentifier, contract, readName string) ConfigError {
 	return ConfigError{
-		Msg: fmt.Sprintf("[no configured reader] read-identifier: %s; contract: %s; read-name: %s;", readIdentifier, contract, readName),
+		Msg: fmt.Sprintf("[contract reader configuration error] no configured reader found for read-name '%s' on contract '%s' (read-identifier: %s). Ensure the method or event is registered in the chain reader configuration", readName, contract, readIdentifier),
 	}
 }
 
 func newUnboundAddressErr(address, contract, readName string) ConfigError {
 	return ConfigError{
-		Msg: fmt.Sprintf("[address not bound] address: %s; contract: %s; read-name: %s;", address, contract, readName),
+		Msg: fmt.Sprintf("[contract reader configuration error] address '%s' is not bound to contract '%s' for read-name '%s'. Bind the address to the contract before attempting reads", address, contract, readName),
 	}
 }
 
@@ -166,7 +166,7 @@ type FilterError struct {
 }
 
 func (e FilterError) Error() string {
-	return fmt.Sprintf("[logpoller filter error] action: %s; err: %s; filter: %+v;", e.Action, e.Err.Error(), e.Filter)
+	return fmt.Sprintf("[log poller filter error] failed during '%s' action: %s; filter details: %+v. Check that the filter configuration matches the expected contract events and addresses", e.Action, e.Err.Error(), e.Filter)
 }
 
 func (e FilterError) Unwrap() error {
@@ -179,7 +179,7 @@ type NoContractExistsError struct {
 }
 
 func (e NoContractExistsError) Error() string {
-	return fmt.Sprintf("%s: contract does not exist at address: %s", e.Err.Error(), e.Address)
+	return fmt.Sprintf("%s: no contract exists at address %s. Verify that the contract has been deployed to this address on the correct chain and that the address is not an externally-owned account (EOA)", e.Err.Error(), e.Address)
 }
 
 func (e NoContractExistsError) Unwrap() error {