diff --git a/requirements.txt b/requirements.txt
old mode 100755
new mode 100644
index eabec4a..000a173
--- a/requirements.txt
+++ b/requirements.txt
@@ -1,4 +1,4 @@
 pandas==0.23.4
-numpy==1.16.0
+numpy==1.22.0
 biopython==1.72
 pysam==0.15.2