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Algorithm for the segmentation of prostate-specific membrane antigen labeling in ciruculating tumor cells of metastatic patients I designed and partially implemented
The patient blood samples analyzed were from clinical studies with IRB protocols 0804009740 and 0707009283 at Cornell Medicine and NCT01718353 phase II clinical trial sponsored by Sanofi for early switch from Docetaxel to Cabazitaxel during the treatment of metastatic castrate-resistant prostate cancer; see the examples of image processing of whole slides in folder Coverslip
Watch my CTC presentation, the second part of this seminar, at the University of Central Florida in 2013: https://youtu.be/kTYyltX9RFg?t=1564
Our image analysis software performs segmentation of the cellular areas with cell surface expression of the prostate-specific membrane antigen to improve the precision of therapy and its customization