Skip to content
View jacgonisa's full-sized avatar

Block or report jacgonisa

Block user

Prevent this user from interacting with your repositories and sending you notifications. Learn more about blocking users.

You must be logged in to block users.

Maximum 250 characters. Please don't include any personal information such as legal names or email addresses. Markdown supported. This note will be visible to only you.
Report abuse

Contact GitHub support about this user’s behavior. Learn more about reporting abuse.

Report abuse
jacgonisa/README.md

Jacob González Isa

PhD Student in Plant Sciences (Bioinformatics) | University of Cambridge

LinkedIn Email Twitter Linktree


Evolution is to me the most fascinating thing in Life.

I love fundamental research - I have been passionate about dissecting the principles of Life and Evolution since I was very young. Academic research allows me to think freely. For that, I chose to research the most paradoxical genomic region: the centromere. This is one of the most important regions in the chromosome and, strikingly, is the region that evolves more rapidly!

I do much wet lab, but I am particularly trained in Bioinformatics. With the power of Computational Biology, I am driven to understand the complexities of Plant Sciences and unlock novel insights in agriculture, sustainability, and ecological preservation.

Last and most importantly, as a first-gen uni student, I am very concerned about the unequal access to the university system between social classes. I actively fight against that problem.

🌱 Plants are my plans for the future!


About Me

I'm a PhD student at the University of Cambridge (Department of Plant Sciences & King's College), funded by the prestigious "la Caixa" Foundation Postgraduate Fellowship. My research focuses on bioinformatics, phylogenomics, and comparative genomics in plant sciences.

  • Working in the Genetic and Epigenetic Inheritance in Plants group (Prof. Henderson)
  • Funded by "la Caixa" Foundation Postgraduate Fellowship - Selected from 1000+ applicants (€120,000+ funding)
  • MSc in Computational Biology| BSc (Hons) in Biochemistry
  • 📊 Pipeline development, Nextflow, HPC computing (SLURM), long-read analysis, and comparative genomics
  • 🎓 Supervisor for "Mathematical and Computational Biology" course at Cambridge

Tech Stack & Tools

Programming Languages

Python R Bash SQL

Bioinformatics & Data Science

Nextflow ETE Toolkit Apache Spark Machine Learning SLURM

Development & Tools

Git Linux Azure SPARQL


Current Research Focus

  • 🧬 Phylogenomics and comparative genomics across plant species
  • 🌿 Genetic and epigenetic inheritance in plants
  • 💻 Bioinformatics pipeline development for genomic analysis
  • 📊 Long-read sequencing analysis and genome assembly
  • 🔍 Metagenomic functional enzyme detection

Selected Publications

Włodzimierz, P., Perez-Roman, E., et al. (including González-Isa, J.) (2025). Cyclical evolution of centromere architecture across 193 eukaryote species. Submitted


GitHub Stats

GitHub Streak

GitHub activity graph

📫 Let's Connect!

I'm always interested in collaborating on exciting projects in computational biology, plant genomics, and bioinformatics. Feel free to reach out!

Email LinkedIn Cambridge Email


💡 "Plants are my plans for the future!"

Profile Views

Pinned Loading

  1. BScThesis_methods BScThesis_methods Public

    An overview of code used in bioinformatic analysis during my BSc Thesis research.

    R

  2. ChIPing ChIPing Public

    Project of ChIP-seq pipeline automatization for "Bioinformatics and Genomic Analysis" course at the University of Seville

    Shell

  3. compara_ontology compara_ontology Public

    Final assignment of the course "Semantic Technologies" of the MSc in Computational Biology at UPM.

    2

  4. JGI_IntroToBioinformatics JGI_IntroToBioinformatics Public

    An Introduction to Computational Biology - UPM Master's Course

    Jupyter Notebook 1 1

  5. StructuralBiology_final_task StructuralBiology_final_task Public

    Final assignment of the course "Computational Structural Biology for Lead Discovery" of the MSc in Computational Biology at UPM.

    Jupyter Notebook

  6. GDAV GDAV Public

    Forked from jhcepas/GDAV

    Materials for the Computational Master subject `Genomic Data Analysis and Visualization`