Skip to content

bwa-mem2 support for reference-flow#5

Open
balabanmetin wants to merge 4 commits intolangmead-lab:mainfrom
balabanmetin:main
Open

bwa-mem2 support for reference-flow#5
balabanmetin wants to merge 4 commits intolangmead-lab:mainfrom
balabanmetin:main

Conversation

@balabanmetin
Copy link

Hello,

I added the functionality to use bwa-mem2 aligner instead of bowtie2 in reference-flow pipeline. The default aligner remains to be bowtie2. I haven't uploaded the bwa-mem2 prebuilt index anywhere (it's large) but if the developers can host them like bowtie2 indices, I'd be happy to upload them to the project's AWS data repo.

Other changes:

  • src/download_1kg_vcf.sh now download tbi files and chrX
  • removed chrY from the CHROM array in the example config file because it lacks 1kg support.

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment

Labels

None yet

Projects

None yet

Development

Successfully merging this pull request may close these issues.

1 participant