Includes all of the analytics done on BRCA data from GHS & UKBB.
The first set of scripts create our case and control groups:
- UKBB_BRCA1.Rmd
- UKBB_BRCA2.Rmd
- GHS_BRCA1.Rmd
- GHS_BRCA2.Rmd
- avengers.R: Pulls out avengers mutations
- avengers_run.R: collect avengers mutations and add to dataframe
- exclusion_ids.Rmd: create list of individuals to exclude from control group
- dualmutations.Rmd: create list of individuals with >1 mutation in BRCA1 or BRCA2
- filter_dataset.R: script to filter genome data for quality
Forest plots:
- brca1_forestplots.Rmd
- brca2_forestplots.Rmd
- forest_plot.R: functions used in above files
- forestplots_ukbb.Rmd: forest plots for fellows' symposium poster
Survival plots:
- operations.Rmd: mutating operation data for use in censoring for survival plots
- survival_analysis_brca1.Rmd
- survival_analysis_brca2.Rmd
- survival_plot.R: functions used in above files
Other:
- case_data.Rmd: link case id #s to actual data
- ghs_censoring_script.R: censoring example for Geisinger analysts